Amah Henry
Imo State University, Nigeria
Title: Genital tract bacteria linked to preterm pre-mature rupture of membrane (pprom) and their antibiotic susceptibility pattern
Biography
Biography: Amah Henry
Abstract
Genital tract infection has been associated with increased risks for preterm premature rupture of the membranes (PPROM). This study was carried out to ascertain the role of genital tract infection in the aetiology of PPROM as well as the antibiotic susceptibility profile of the incriminating pathogens. METHODS: A total of 102 pregnant women presented with PPROM between 24 weeks and 37 weeks of gestation and 102 control cases were enrolled while attending prenatal clinic of the federal medical centre, Owerri. The sociodemographic characteristics of the study population was taken and microbial flora were isolated using standard bacteriological methods. Disc susceptibility test was performed according to NCCLS methods. RESULTS: Pathogens were isolated in 85 patients, giving a recovery rate of 83.3%. The common pathogens include Escherichia coli (23.5%), Staphylococcus aureus (20.6%) Streptococcus spp (16.7%) and Candida albican (13.7%). Levofloxacin was the most effective antibiotics against all the isolated pathogens while ampicillin-cloxacillin was the least active. CONCLUSION: The timely detection and administration of ceftriaxone erythromycin, cefuroxime or augmentin were suggested for conservative management of PPROM.