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Ali

The Foundation University, Pakistan

Title: Is Stenotrophomonas maltophilia heading towards pan-drug resistance?

Biography

Biography: Ali

Abstract

Abstract: Objective: The objective of this study is to determine the antimicrobial resistance pattern of Stenotrophomonas maltophilia isolated in a tertiary care setting and frequency of multi, extensively and pan drug resistant Stenotrophomonas maltophilia. Material and Methods: A quasi-experimental study was carried out in Microbiology Department, Fauji Foundation Hospital, Rawalpindi, from January 2015 to June 2015. Isolates were identified as Stenotrophomonas maltophilia using standard microbiological techniques and the antimicrobial resistance was carried out using Kirby-Bauer disc diffusion against various antimicrobials. Data was analyzed using SPSS(software version 21). Results: Ninety isolates were confirmed as Stenotrophomonas maltophilia. Pus(33.33%) and urine(24.44%) were the most common specimens from which this bacterium was isolated. Antimicrobial resistance pattern has shown high percentage of resistance to many antimicrobials with exception to azetronam, minocycline, polymyxin B and colistin. Conclusion: Stenotrophomonas maltophilia isolates from our setup were resistant to antimicrobial agents used in the study. It is predicted that the infections caused by this bacterium shall be difficult to treat in near future due to resistance to these antimicrobial agents. Though at this point no pan drug resistant Stenotrophomonas maltophilia is reported but the resistance pattern suggests that pan drug resistant strains may arise in near future and when the time comes only newer antimicrobials can provide the answer. Keywords: antimicrobial resistance, pan drug resistance(PDR), Stenotrophomonas maltophilia.