Bacteriology and Infectious Diseases

Biography

Biography: Dima Dandachi

Abstract

Clinical infection due to oligella urethralis has been rarely reported in the literature probably due to misidentification or uncertainty of its pathogenicity. The data of patients with Oligella Urethralis infection were collected from 4 hospitals in Chicago area between January 2010 and December 2015. There were 16 cases identified, all were adults except for 1 patient who was 14 years old, mean age of 58.4 (14-91), 6 men (37.5%) and 10 females (62.5%). Source of infection was urinary tract infection in 9 out of 16 patients (56.2%). One patient had Oligella Urethralis bacteremia with no identified source, urine culture failed to grow Oligella, renal ultrasound did not show any sign of obstruction. One patient had labial abscess and one had axillary abscess that grew Oligella Urethralis. Contrary to previously reported risk factors being cancer and urinary tract abnormalities, no significant underlying immunosuppression was identified in our patients except that 56.2% had underlying Diabetes Mellitus; 2 had active cancer. No urinary obstruction was identified; however 2 patients had urinary incontinence. Antimicrobial susceptibility is not done routinely on Oligella Urethralis isolates because of lack of standardized methods for susceptibility testing per Clinical and Laboratory Standardized Institute, 7 out of 16 isolates were resistant to quinolones, 2 were resistant to Aztreonam, and all were sensitive to all B–lactam antibiotics. All patients were treated with antibiotics and recovered except for 1 patient who died secondary to sepsis, Oligella bacteremia.Our review suggests that further studies are necessary to understand this bacterium’s clinical significance.